Minimum lumen diameter of femoral arteries at baseline and 32 days follow-up. FREEWAY™ 035 DEB inhibited fibrin accumulation in the intima and media, leading to significantly less constrictive remodeling and reduced neointimal hyperplasia of the injured vessel compared to uncoated balloons.
FREEWAY™ Preclinical Program
Domestic swine femoral arteries (n = 54) underwent percutaneous overstretch balloon dilation with the Freeway™ 035 DEB, controlled by optical coherence tomography (OCT). Paclitaxel tissue uptake was measured at 1h, 1 and 3 days.